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Nano-bio-engineered silk matrix based devices for molecular bioanalysis.
Sammi, Aditi; Mahapatra, Supratim; Kumar, Rahul; Chandra, Pranjal.
Afiliação
  • Sammi A; Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
  • Divya; Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
  • Mahapatra S; Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
  • Kumar R; Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
  • Chandra P; Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, India.
Biotechnol Bioeng ; 119(3): 784-806, 2022 03.
Article em En | MEDLINE | ID: mdl-34958139
ABSTRACT
Silk is a fibrous protein, has been a part of human lives for centuries,  and was used as suture and textile material. Silk is mainly produced by the members of certain arthropods such as spiders, butterflies, mites, and moths. However, recent technological advances have revolutionized silk as a biomaterial for various applications ranging from heat sensors to robust fibers. The biocompatibility, mechanical resilience, and biodegradability of the material make it a suitable candidate for biomaterials. Silk can also be easily converted into several morphological forms, including fibers, films, sponges, and hydrogels. Provided these abilities, silk have received excellent traction from scientists worldwide for various developments, one of them being its use as a bio-sensor. The diversity of silk materials offers various options, giving scientists the freedom to choose from and personalize them as per their needs. In this review, we foremost look upon the composition, production, properties, and various morphologies of silk. The numerous applications of silk and its derivatives for fabricating biosensors to detect small molecules, macromolecules, and cells have been explored comprehensively. Also, the data from various globally developed sensors using silk have been described into organized tables for each category of molecules, along with their important analytical details.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aranhas / Borboletas Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aranhas / Borboletas Limite: Animals Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia