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Biomanufacturing in low Earth orbit for regenerative medicine.
Sharma, Arun; Clemens, Rachel A; Garcia, Orquidea; Taylor, D Lansing; Wagner, Nicole L; Shepard, Kelly A; Gupta, Anjali; Malany, Siobhan; Grodzinsky, Alan J; Kearns-Jonker, Mary; Mair, Devin B; Kim, Deok-Ho; Roberts, Michael S; Loring, Jeanne F; Hu, Jianying; Warren, Lara E; Eenmaa, Sven; Bozada, Joe; Paljug, Eric; Roth, Mark; Taylor, Donald P; Rodrigue, Gary; Cantini, Patrick; Smith, Amelia W; Giulianotti, Marc A; Wagner, William R.
Afiliação
  • Sharma A; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address: arun.sharma@cshs.
  • Clemens RA; Axiom Space, Inc., Houston, TX, USA.
  • Garcia O; Johnson & Johnson 3D Printing Innovation & Customer Solutions, Johnson & Johnson Services, Inc., Irvine, CA, USA.
  • Taylor DL; University of Pittsburgh Drug Discovery Institute and Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Wagner NL; LambdaVision Inc., Farmington, CT, USA.
  • Shepard KA; California Institute for Regenerative Medicine, Oakland, CA, USA.
  • Gupta A; Axiom Space, Inc., Houston, TX, USA.
  • Malany S; Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, FL, USA.
  • Grodzinsky AJ; Departments of Biological Engineering, Mechanical Engineering and Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Kearns-Jonker M; Department of Pathology and Human Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA.
  • Mair DB; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Kim DH; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Roberts MS; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA.
  • Loring JF; Scripps Research Institute, San Diego, CA, USA.
  • Hu J; Center for Computational Health IBM Research, Yorktown Heights, New York, NY, USA.
  • Warren LE; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA.
  • Eenmaa S; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA.
  • Bozada J; Joseph M. Katz Graduate School of Business, University of Pittsburgh, Pittsburgh, PA, USA.
  • Paljug E; Joseph M. Katz Graduate School of Business, University of Pittsburgh, Pittsburgh, PA, USA.
  • Roth M; Pittsburgh, PA, USA.
  • Taylor DP; The Ohio State University, Columbus, OH, USA.
  • Rodrigue G; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA.
  • Cantini P; McGowan Institute for Regenerative Medicine, Pittsburgh, PA, USA.
  • Smith AW; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA.
  • Giulianotti MA; Center for the Advancement of Science in Space, Inc, Melbourne, FL, USA. Electronic address: mgiulianotti@issnationallab.org.
  • Wagner WR; McGowan Institute for Regenerative Medicine, Pittsburgh, PA, USA; Departments of Surgery, Bioengineering, Chemical Engineering, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: wagnerwr@upmc.edu.
Stem Cell Reports ; 17(1): 1-13, 2022 01 11.
Article em En | MEDLINE | ID: mdl-34971562
ABSTRACT
Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Medicina Regenerativa / Meio Ambiente Extraterreno / Manufaturas Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Materiais Biocompatíveis / Medicina Regenerativa / Meio Ambiente Extraterreno / Manufaturas Limite: Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2022 Tipo de documento: Article