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A prospective, interventional study comparing the outcomes of macular hole surgery in eyes randomized to C3F8, C2F6, or SF6 gas tamponade.
Rishi, Pukhraj; Rishi, Ekta; Bhende, Pramod; Bhende, Muna; Kandle, Kaustubh; Attiku, Yamini; Roy, Krishna Kanta; Shelke, Komal; Madaan, Sushant.
Afiliação
  • Rishi P; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India. docrishi@yahoo.co.in.
  • Rishi E; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Bhende P; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Bhende M; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Kandle K; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Attiku Y; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Roy KK; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Shelke K; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
  • Madaan S; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai, Tamil Nadu, 600006, India.
Int Ophthalmol ; 42(5): 1515-1521, 2022 May.
Article em En | MEDLINE | ID: mdl-34997371
ABSTRACT

PURPOSE:

Analysis of outcomes of macular hole (MH) surgery using 12% C3F8, 16% C2F6, or 18% SF6 as randomized gas tamponading agent.

METHODS:

This is a prospective, randomized, interventional study of 159 eyes with idiopathic MH undergoing 23/25G pars-plana vitrectomy with internal limiting membrane peeling and gas tamponade. Eyes were stratified into two groups Group I (MH < 800 µ) and group II (MH > 800 µ) according to MH apical diameter. Eyes in group I were randomized to receive either 18% SF6, 16% C2F6, or 12% C3F8. Eyes in group II were randomized to either 16% C2F6 or 12% C3F8. Clinical details, MH parameters on optical coherence tomography, surgical details and complications were analyzed. Outcome measures were type of hole closure (I/II), best corrected visual acuity, intraocular pressure, and cataract progression.

RESULTS:

In Group I (n = 139), type 1 closure was achieved in 107 (77%) eyes. Type 1 closure rates in group I per gas tamponade were as follows SF6 (70%), C2F6 (80%), C3F8 (78%) (p = 0.503, chi-square test for independence). There was no statistical difference in MH closure rates between SF6 and C2F6 (p = 0.134), SF6 and C3F8 (p = 0.186), and C2F6 and C3F8 (p = 0.373). In Group II (n = 20), type 1 closure was achieved in 12 (60%) eyes. Type 1 closure rates in group II per gas tamponade were as follows C2F6 (75%), C3F8 (50%) (p = 0.132, Two proportion Z test). Mean follow-up after surgery was 2.66 ± 2.74 months.

CONCLUSION:

Given the similar outcomes of using 18% SF6, 16% C2F6, or 12% C3F8 in idiopathic macular hole surgery, the advantage of using a shorter acting tamponade translates into earlier recovery and rehabilitation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perfurações Retinianas / Fluorocarbonos Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Int Ophthalmol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perfurações Retinianas / Fluorocarbonos Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Int Ophthalmol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia