Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus <i>Aspergillus puniceus</i>.

Liu, Cheng-Mei; Yao, Fei-Hua; Lu, Xin-Hua; Zhang, Xue-Xia; Luo, Lian-Xiang; Liang, Xiao; Qi, Shu-Hua

Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus Aspergillus puniceus.

Liu, Cheng-Mei; Yao, Fei-Hua; Lu, Xin-Hua; Zhang, Xue-Xia; Luo, Lian-Xiang; Liang, Xiao; Qi, Shu-Hua.

Afiliação

Liu CM; CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Yao FH; University of Chinese Academy of Sciences, Beijing 100049, China.
Lu XH; CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Zhang XX; University of Chinese Academy of Sciences, Beijing 100049, China.
Luo LX; New Drug Research & Development Co., Ltd., North China Pharmaceutical Group Corporation, Shijiazhuang 050015, China.
Liang X; New Drug Research & Development Co., Ltd., North China Pharmaceutical Group Corporation, Shijiazhuang 050015, China.
Qi SH; The Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang 524023, China.

Mar Drugs ; 20(1)2022 Jan 17.

Article em En | MEDLINE | ID: mdl-35049933

Assuntos

Alcaloides/farmacologia; Antibacterianos/farmacologia; Antineoplásicos/farmacologia; Aspergillus; Isoquinolinas/farmacologia; Proteínas Tirosina Fosfatases/antagonistas & inibidores; Alcaloides/química; Animais; Antibacterianos/química; Antineoplásicos/química; Organismos Aquáticos; Linhagem Celular Tumoral/efeitos dos fármacos; Humanos; Concentração Inibidora 50; Isoquinolinas/química; Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos; Testes de Sensibilidade Microbiana

Palavras-chave

Aspergillus puniceus; antibacterial; cytotoxicity; deep-sea-derived fungus; isoquinoline alkaloid; protein tyrosine phosphatase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aspergillus / Proteínas Tirosina Fosfatases / Alcaloides / Isoquinolinas / Antibacterianos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Mar Drugs Assunto da revista: BIOLOGIA / FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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