Oxidative Stress and X-ray Exposure Levels-Dependent Survival and Metabolic Changes in Murine HSPCs.

Karabulutoglu, Melis; Finnon, Rosemary; Cruz-Garcia, Lourdes; Hill, Mark A; Badie, Christophe

Karabulutoglu, Melis; Finnon, Rosemary; Cruz-Garcia, Lourdes; Hill, Mark A; Badie, Christophe.

Afiliação

Karabulutoglu M; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Radiation, Chemical and Environmental Hazards Directorate (RCE, Formally CRCE), UK Health Security Agency (Formerly Public Health England), Chilton, Didcot, Oxon OX11 0RQ, UK.
Finnon R; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK.
Cruz-Garcia L; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Radiation, Chemical and Environmental Hazards Directorate (RCE, Formally CRCE), UK Health Security Agency (Formerly Public Health England), Chilton, Didcot, Oxon OX11 0RQ, UK.
Hill MA; Cancer Mechanisms and Biomarkers Group, Radiation Effects Department, Radiation, Chemical and Environmental Hazards Directorate (RCE, Formally CRCE), UK Health Security Agency (Formerly Public Health England), Chilton, Didcot, Oxon OX11 0RQ, UK.
Badie C; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK.

Antioxidants (Basel) ; 11(1)2021 Dec 22.

Article em En | MEDLINE | ID: mdl-35052515

Palavras-chave

HSPCs; acute myeloid leukaemia; hypoxia; ionising radiation; metabolism; mitochondrial dysfunction; oxidative stress; radiation leukemogenesis; reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Antioxidants (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

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