Zebrafish drug screening identifies candidate therapies for neuroprotection after spontaneous intracerebral haemorrhage.

Crilly, Siobhan; Parry-Jones, Adrian; Wang, Xia; Selley, Julian N; Cook, James; Tapia, Victor S; Anderson, Craig S; Allan, Stuart M; Kasher, Paul R

Crilly, Siobhan; Parry-Jones, Adrian; Wang, Xia; Selley, Julian N; Cook, James; Tapia, Victor S; Anderson, Craig S; Allan, Stuart M; Kasher, Paul R.

Afiliação

Crilly S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Parry-Jones A; Geoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance and The University of Manchester, Manchester M6 8HD, UK.
Wang X; Geoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance and The University of Manchester, Manchester M6 8HD, UK.
Selley JN; Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Cook J; Manchester Centre for Clinical Neurosciences, Salford Royal, NHS Foundation Trust, Manchester Academic Health Science Centre, Stott Lane, Salford M6 8HD, UK.
Tapia VS; The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia.
Anderson CS; The Biological Mass Spectrometry Core Research Facility, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.
Allan SM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Kasher PR; Geoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance and The University of Manchester, Manchester M6 8HD, UK.

Dis Model Mech ; 15(3)2022 03 01.

Article em En | MEDLINE | ID: mdl-35098999

Assuntos

Neuroproteção; Peixe-Zebra; Animais; Hemorragia Cerebral/tratamento farmacológico; Avaliação Pré-Clínica de Medicamentos; Humanos; Larva; Proteômica

Palavras-chave

ACE inhibitors; Drug screen; Intracerebral haemorrhage; Stroke; Zebrafish

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Neuroproteção Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Dis Model Mech Assunto da revista: MEDICINA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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