Lower Airway Nitrogen Oxide Levels in Children with Primary Ciliary Dyskinesia Is Linked to Neutrophilic Inflammation.
J Pediatr
; 244: 230-233, 2022 05.
Article
em En
| MEDLINE
| ID: mdl-35120987
ABSTRACT
Treatment of primary ciliary dyskinesia pulmonary exacerbations resulted in an increase in sputum nitric oxide (NO) metabolites and decrease in neutrophilic inflammation. The association between the 2 suggests that neutrophilic inflammation contributes to airway NO deficiency in primary ciliary dyskinesia and that reducing inflammation may lead to improved airway NO homeostasis. TRIAL REGISTRY ClinicalTrials.gov NCT01155115.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos da Motilidade Ciliar
/
Óxido Nítrico
Limite:
Child
/
Humans
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
2022
Tipo de documento:
Article