Lysosomal gene Hexb displays haploinsufficiency in a knock-in mouse model of Alzheimer's disease.
IBRO Neurosci Rep
; 12: 131-141, 2022 Jun.
Article
em En
| MEDLINE
| ID: mdl-35146484
AD, Alzheimer's disease; APP, amyloid precursor protein; Alzheimer's disease; AppNL-G-F/NL-G-F; Aß, amyloid beta; CD68, cluster of differentiation 68; Dementia; ELISA, enzyme-linked immunosorbent assay; GFAP, glial fibrillary acidic protein; HEXB, ß-hexosaminidase ß subunit; Hexb; IBA1, ionised calcium binding adaptor molecule 1; IL, interleukin; Knock-in; LAMP1, lysosome associated membrane protein 1; LSDs, lysosomal storage disorders; Lysosome; PBS, phosphate buffered saline; TREM2, triggering receptor expressed on myeloid cells 2; ß-hexosaminidase
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
IBRO Neurosci Rep
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Austrália