Gene-Directed Enzyme/Prodrug Therapy of Rat Brain Tumor Mediated by Human Mesenchymal Stem Cell Suicide Gene Extracellular Vesicles In Vitro and In Vivo.

Tibensky, Miroslav; Jakubechova, Jana; Altanerova, Ursula; Pastorakova, Andrea; Rychly, Boris; Baciak, Ladislav; Mravec, Boris; Altaner, Cestmir

Tibensky, Miroslav; Jakubechova, Jana; Altanerova, Ursula; Pastorakova, Andrea; Rychly, Boris; Baciak, Ladislav; Mravec, Boris; Altaner, Cestmir.

Afiliação

Tibensky M; Institute of Physiology, Faculty of Medicine, Comenius University, 81372 Bratislava, Slovakia.
Jakubechova J; Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, 84505 Bratislava, Slovakia.
Altanerova U; Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, 84505 Bratislava, Slovakia.
Pastorakova A; Department of Stem Cell Preparation, St. Elisabeth Cancer Institute, 84505 Bratislava, Slovakia.
Rychly B; Department of Stem Cell Preparation, St. Elisabeth Cancer Institute, 84505 Bratislava, Slovakia.
Baciak L; Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, 81108 Bratislava, Slovakia.
Mravec B; Alpha Medical, Ltd., 82606 Bratislava, Slovakia.
Altaner C; Central Laboratories, Slovak University of Technology, 81237 Bratislava, Slovakia.

Cancers (Basel) ; 14(3)2022 Jan 31.

Article em En | MEDLINE | ID: mdl-35159002

Palavras-chave

curative effect; gene-directed enzyme prodrug therapy; intranasal application; mesenchymal stem cells; rat glioblastoma; suicide gene extracellular vesicles; yCD::UPRT-MSC-EVs

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Eslováquia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google