Innovative developments and emerging technologies in RNA therapeutics.

Halloy, François; Biscans, Annabelle; Bujold, Katherine E; Debacker, Alexandre; Hill, Alyssa C; Lacroix, Aurélie; Luige, Olivia; Strömberg, Roger; Sundstrom, Linda; Vogel, Jörg; Ghidini, Alice

Halloy, François; Biscans, Annabelle; Bujold, Katherine E; Debacker, Alexandre; Hill, Alyssa C; Lacroix, Aurélie; Luige, Olivia; Strömberg, Roger; Sundstrom, Linda; Vogel, Jörg; Ghidini, Alice.

Afiliação

Halloy F; Department of Paediatrics, Medical Sciences Division, University of Oxford, Oxford, UK.
Biscans A; Oligonucleotide Chemistry, Discovery Sciences, BioPharmaceuticals R&d, AstraZeneca, Gothenburg, Sweden.
Bujold KE; Department of Chemistry & Chemical Biology, McMaster University, (Ontario), Canada.
Debacker A; MiNA Therapeutics, Translation & Innovation Hub, London, UK.
Hill AC; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, Eth Zürich, Zürich, Switzerland.
Lacroix A; Sixfold Bioscience, Translation & Innovation Hub, London, UK.
Luige O; Department of Biosciences and Nutrition, Karolinska Institutet, Sweden.
Strömberg R; Department of Biosciences and Nutrition, Karolinska Institutet, Sweden.
Sundstrom L; Mechanistic and Structural Biology, Discovery Sciences, BioPharmaceuticals R&d, AstraZeneca, Gothenburg, Sweden.
Vogel J; Helmholtz Institute for RNA-based Infection Research (Hiri), Helmholtz Center for Infection Research (Hzi), Würzburg, Germany.
Ghidini A; RNA Biology Group, Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.

RNA Biol ; 19(1): 313-332, 2022.

Article em En | MEDLINE | ID: mdl-35188077

Assuntos

Terapia Genética; RNA/genética; RNA/uso terapêutico; Pesquisa; Animais; Biotecnologia; Técnicas de Transferência de Genes; Terapia Genética/métodos; Terapia Genética/tendências; Humanos; Nanotecnologia; Oligonucleotídeos Antissenso; RNA/química; RNA Mensageiro; RNA Interferente Pequeno; Pesquisa/tendências

Palavras-chave

PROTAC; RNA-therapeutics; antisense; delivery; nucleic acid technologies; oligonucleotide based artificial ribonucleases; saRNA; siRNA; viral RNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pesquisa / RNA / Terapia Genética Limite: Animals / Humans Idioma: En Revista: RNA Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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