Repetitive expanded T-cell receptor clonotypes impart the classic T helper 2 Sézary cell phenotype.
Br J Dermatol
; 187(2): 265-267, 2022 08.
Article
em En
| MEDLINE
| ID: mdl-35191024
ABSTRACT
Six out of 12 Sézary patients shared one clonotype (TRAV13-1*01-TRAJ49*01-TRBV20-1*01-TRBJ2-3*01). TRBV20-1*01 (also known as Vb2) that binds toxic shock syndrome toxin-1 was utilized by Sézary cells among half of the cohort, which would be expected for a common unifying origin.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Síndrome de Sézary
Limite:
Humans
Idioma:
En
Revista:
Br J Dermatol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos