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NanoSIMS Imaging Reveals the Impact of Ligand-ASO Conjugate Stability on ASO Subcellular Distribution.
Kay, Emma; Stulz, Rouven; Becquart, Cécile; Lovric, Jelena; Tängemo, Carolina; Thomen, Aurélien; Bazdarevic, Dzenita; Najafinobar, Neda; Dahlén, Anders; Pielach, Anna; Fernandez-Rodriguez, Julia; Strömberg, Roger; Ämmälä, Carina; Andersson, Shalini; Kurczy, Michael.
Afiliação
  • Kay E; Mechanistic and Structural Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Stulz R; Department of Biosciences and Nutrition, Karolinska Institutet, SE-141 83 Huddinge, Sweden.
  • Becquart C; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Lovric J; DMPK, Early Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Tängemo C; DMPK, Early Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Thomen A; Department of Chemistry and Molecular Biology, University of Gothenburg, SE 412 96 Gothenburg, Sweden.
  • Bazdarevic D; DMPK, Early Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Najafinobar N; Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Dahlén A; Department of Chemistry and Molecular Biology, University of Gothenburg, SE 412 96 Gothenburg, Sweden.
  • Pielach A; Bioscience, Early Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Fernandez-Rodriguez J; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Strömberg R; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Gothenburg, Sweden.
  • Ämmälä C; Centre for Cellular Imaging, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.
  • Andersson S; Centre for Cellular Imaging, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.
  • Kurczy M; Department of Biosciences and Nutrition, Karolinska Institutet, SE-141 83 Huddinge, Sweden.
Pharmaceutics ; 14(2)2022 Feb 21.
Article em En | MEDLINE | ID: mdl-35214195
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceutics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suécia