Prodrugs of Persulfide and Sulfide: Is There a Pharmacological Difference between the Two in the Context of Rapid Exchanges among Various Sulfur Species In Vivo?

Yu, Bingchen; Kang, Ting; Xu, Yuan; Liu, Yiqing; Ma, Yaru; Ke, Bowen

Yu, Bingchen; Kang, Ting; Xu, Yuan; Liu, Yiqing; Ma, Yaru; Ke, Bowen.

Afiliação

Yu B; Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.
Kang T; Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P. R. China.
Xu Y; Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P. R. China.
Liu Y; Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P. R. China.
Ma Y; Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P. R. China.
Ke B; Department of Anesthesiology, Laboratory of Anesthesia and Critical Care Medicine, National-Local Joint Engineering Research Centre of Translational Medicine of Anesthesiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P. R. China.

Angew Chem Int Ed Engl ; 61(20): e202201668, 2022 05 09.

Article em En | MEDLINE | ID: mdl-35218121

Assuntos

Sulfeto de Hidrogênio; Pró-Fármacos; Cisteína/química; Sulfeto de Hidrogênio/química; Pró-Fármacos/química; Sulfetos/química; Enxofre/metabolismo

Palavras-chave

Hydrogen Persulfide Prodrug; Hydrogen Sulfide Prodrug; Sulfur Chemistry; Sulfur Species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Sulfeto de Hidrogênio Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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