Inhibition of Src improves cardiac fibrosis in AngII-induced hypertrophy by regulating the expression of galectin-3.

Zhong, Xiao; Song, Ziguang; Ning, Zhongping; Wu, Jinrong; Song, Xiang

Zhong, Xiao; Song, Ziguang; Ning, Zhongping; Wu, Jinrong; Song, Xiang.

Afiliação

Zhong X; Department of Cardiology, the Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Song Z; Department of Cardiology, the Fourth Affiliated Hospital, Harbin Medical University, Heilongjiang, China.
Ning Z; Shanghai University of Medicine & Health Sciences, Zhoupu Hospital, Shanghai, China.
Wu J; Department of Anesthesiology, The First Affiliated Hospital, Harbin Medical University, Heilongjiang, China. Electronic address: wg9198@163.com.
Song X; Shanghai University of Medicine & Health Sciences, Zhoupu Hospital, Shanghai, China. Electronic address: song761231@sina.com.

Microvasc Res ; 142: 104347, 2022 07.

Article em En | MEDLINE | ID: mdl-35231451

Assuntos

Angiotensina II; Cardiomegalia; Galectina 3; Quinases da Família src; Angiotensina II/farmacologia; Animais; Cardiomegalia/induzido quimicamente; Cardiomegalia/metabolismo; Cardiomegalia/prevenção & controle; Fibrose; Galectina 3/biossíntese; Galectina 3/genética; Galectina 3/metabolismo; Camundongos; Camundongos Knockout; Miócitos Cardíacos/metabolismo; Miócitos Cardíacos/patologia; Quinases da Família src/antagonistas & inibidores; Quinases da Família src/metabolismo

Palavras-chave

Angiotensin II; Cardiac fibrosis; Cardiac hypertrophy; Galectin-3; Src

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Angiotensina II / Cardiomegalia / Quinases da Família src / Galectina 3 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Microvasc Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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