Systematic optimization of host-directed therapeutic targets and preclinical validation of repositioned antiviral drugs.

Xie, Dafei; He, Song; Han, Lu; Wu, Lianlian; Huang, Hai; Tao, Huan; Zhou, Pingkun; Shi, Xunlong; Bai, Hui; Bo, Xiaochen

Xie, Dafei; He, Song; Han, Lu; Wu, Lianlian; Huang, Hai; Tao, Huan; Zhou, Pingkun; Shi, Xunlong; Bai, Hui; Bo, Xiaochen.

Afiliação

Xie D; Beijing Institute of Radiation Medicine, Beijing, China, 100850.
He S; Beijing Institute of Radiation Medicine, Beijing, China, 100850.
Han L; Beijing Institute of Pharmacology and Toxicology, Beijing, China, 100850.
Wu L; Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China, 300072.
Huang H; Department of Biological Medicines, School of Pharmacy, Fudan University, Shanghai, China, 201203.
Tao H; Beijing Institute of Radiation Medicine, Beijing, China, 100850.
Zhou P; Beijing Institute of Radiation Medicine, Beijing, China, 100850.
Shi X; Department of Biological Medicines, School of Pharmacy, Fudan University, Shanghai, China, 201203.
Bai H; BioMap (Beijing) Intelligence Technology Limited, Beijing, China, 100005.
Bo X; Beijing Institute of Radiation Medicine, Beijing, China, 100850.

Brief Bioinform ; 23(3)2022 05 13.

Article em En | MEDLINE | ID: mdl-35238349

Assuntos

Antivirais; Vírus da Influenza A; Antivirais/farmacologia; Antivirais/uso terapêutico; Dextrometorfano; Humanos; Vírus da Influenza A/genética

Palavras-chave

antiviral drugs; drug repositioning; drug target; network analysis; virushost interactome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Brief Bioinform Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2022 Tipo de documento: Article

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