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3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells.
Wang, Zhiqiang; McWilliams-Koeppen, Helen P; Reza, Hernan; Ostberg, Julie R; Chen, Wuyang; Wang, Xiuli; Huynh, Christian; Vyas, Vibhuti; Chang, Wen-Chung; Starr, Renate; Wagner, Jamie R; Aguilar, Brenda; Yang, Xin; Wu, Xiwei; Wang, Jinhui; Chen, Wei; Koelker-Wolfe, Ellery; Seet, Christopher S; Montel-Hagen, Amélie; Crooks, Gay M; Forman, Stephen J; Brown, Christine E.
Afiliação
  • Wang Z; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA. Electronic address: zhwang@coh.org.
  • McWilliams-Koeppen HP; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Reza H; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Ostberg JR; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Chen W; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Wang X; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Huynh C; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Vyas V; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Chang WC; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Starr R; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Wagner JR; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Aguilar B; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Yang X; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Wu X; Integrative Genomics Core, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Wang J; Integrative Genomics Core, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Chen W; Integrative Genomics Core, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Koelker-Wolfe E; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Seet CS; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Broad Stem Cell Research Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, UCLA, Los Angeles,
  • Montel-Hagen A; Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
  • Crooks GM; Broad Stem Cell Research Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Department of Pathology & Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, U
  • Forman SJ; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA.
  • Brown CE; Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratories, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA, USA. Electronic address: cbrown@coh.org.
Cell Stem Cell ; 29(4): 515-527.e8, 2022 04 07.
Article em En | MEDLINE | ID: mdl-35278370
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Receptores de Antígenos Quiméricos Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Receptores de Antígenos Quiméricos Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2022 Tipo de documento: Article