Temporal and brain region-specific elevations of soluble Amyloid-ß<sub>40-42</sub> in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Tallino, Savannah; Winslow, Wendy; Bartholomew, Samantha K; Velazquez, Ramon

Temporal and brain region-specific elevations of soluble Amyloid-ß_40-42 in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Tallino, Savannah; Winslow, Wendy; Bartholomew, Samantha K; Velazquez, Ramon.

Afiliação

Tallino S; Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.
Winslow W; School of Life Sciences, Arizona State University, Tempe, Arizona, USA.
Bartholomew SK; Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.
Velazquez R; Arizona State University-Banner Neurodegenerative Disease Research Center at the Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

Aging Cell ; 21(4): e13590, 2022 04.

Article em En | MEDLINE | ID: mdl-35290711

Assuntos

Doença de Alzheimer; Síndrome de Down; Doença de Alzheimer/patologia; Peptídeos beta-Amiloides/metabolismo; Precursor de Proteína beta-Amiloide/metabolismo; Animais; Encéfalo/metabolismo; Modelos Animais de Doenças; Síndrome de Down/metabolismo; Feminino; Humanos; Masculino; Camundongos; Camundongos Transgênicos

Palavras-chave

Amyloid-ß40-42; Ts65Dn; basal forebrain; down syndrome; hippocampus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Down / Doença de Alzheimer Limite: Animals / Female / Humans / Male Idioma: En Revista: Aging Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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