Prediction of hERG inhibition of drug discovery compounds using biomimetic HPLC measurements.

Stergiopoulos, Chrysanthos; Tsopelas, Fotios; Valko, Klara

Stergiopoulos, Chrysanthos; Tsopelas, Fotios; Valko, Klara.

Afiliação

Stergiopoulos C; Laboratory of Inorganic and Analytical Chemistry, School of Chemical Engineering, National Technical University of Athens.
Tsopelas F; Laboratory of Inorganic and Analytical Chemistry, School of Chemical Engineering, National Technical University of Athens.
Valko K; Bio-Mimetic Chromatography Ltd. Stevenage, Herts, United Kingdom.

ADMET DMPK ; 9(3): 191-207, 2021.

Article em En | MEDLINE | ID: mdl-35300361

Palavras-chave

AGP binding; Cardiotoxicity; IAM binding; Proarrhythmia; QT Prolongation; Torsades de Pointes; hERG inhibition

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: ADMET DMPK Ano de publicação: 2021 Tipo de documento: Article

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