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High-throughput multiplex analysis of mAb aggregates and charge variants by automated two-dimensional size exclusion-cation exchange chromatography coupled to mass spectrometry.
Lambiase, Giulia; Inman, Sophie E; Muroni, Maurizio; Lindo, Vivian; Dickman, Mark J; James, David C.
Afiliação
  • Lambiase G; Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, United Kingdom; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Cambridge, United Kingdom.
  • Inman SE; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Cambridge, United Kingdom.
  • Muroni M; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Cambridge, United Kingdom.
  • Lindo V; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Cambridge, United Kingdom. Electronic address: viv.lindo@astrazeneca.com.
  • Dickman MJ; Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, United Kingdom. Electronic address: m.dickman@sheffield.ac.uk.
  • James DC; Department of Chemical and Biological Engineering, University of Sheffield, Sheffield, United Kingdom. Electronic address: d.c.james@sheffield.ac.uk.
J Chromatogr A ; 1670: 462944, 2022 May 10.
Article em En | MEDLINE | ID: mdl-35344792
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Idioma: En Revista: J Chromatogr A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Idioma: En Revista: J Chromatogr A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido