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Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Jiang, Yi Xiao; Cao, Qin; Sawaya, Michael R; Abskharon, Romany; Ge, Peng; DeTure, Michael; Dickson, Dennis W; Fu, Janine Y; Ogorzalek Loo, Rachel R; Loo, Joseph A; Eisenberg, David S.
Afiliação
  • Jiang YX; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, and Molecular Biology Institute, UCLA, Los Angeles, CA, USA.
  • Cao Q; Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA.
  • Sawaya MR; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, and Molecular Biology Institute, UCLA, Los Angeles, CA, USA.
  • Abskharon R; Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA.
  • Ge P; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai, China.
  • DeTure M; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, and Molecular Biology Institute, UCLA, Los Angeles, CA, USA.
  • Dickson DW; Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA.
  • Fu JY; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, and Molecular Biology Institute, UCLA, Los Angeles, CA, USA.
  • Ogorzalek Loo RR; Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA.
  • Loo JA; Departments of Chemistry and Biochemistry and Biological Chemistry, UCLA-DOE Institute, and Molecular Biology Institute, UCLA, Los Angeles, CA, USA.
  • Eisenberg DS; Howard Hughes Medical Institute, UCLA, Los Angeles, CA, USA.
Nature ; 605(7909): 304-309, 2022 05.
Article em En | MEDLINE | ID: mdl-35344984
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Amiloide / Proteínas de Membrana / Proteínas do Tecido Nervoso Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a DNA / Degeneração Lobar Frontotemporal / Amiloide / Proteínas de Membrana / Proteínas do Tecido Nervoso Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos