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Molecular characterization of chikungunya virus from the first cluster of patients during the 2020 outbreak in Chad.
Yonga, Martial Gide; Yandai, Fissou Henry; Sadeuh-Mba, Serge; Abdallah, Alsadick Haroun; Ouapi, Diane; Gamougam, Kadidja; Abanda, Ngu Njei; Endengue-Zanga, Marie Claire; Demanou, Maurice; Njouom, Richard.
Afiliação
  • Yonga MG; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon.
  • Yandai FH; Laboratory for Hemorrhagic and Respiratory Viruses, N'Djamena Mobile Laboratory, N'Djamena, Chad.
  • Sadeuh-Mba S; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon.
  • Abdallah AH; Ministry of Public Health, N'Djamena, Chad.
  • Ouapi D; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon.
  • Gamougam K; CHU de Référence Nationale, N'Djamena, Chad.
  • Abanda NN; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon.
  • Endengue-Zanga MC; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon.
  • Demanou M; Inter-Country Support Team West Africa, World Health Organization, Ouagadougou, Burkina Faso.
  • Njouom R; Virology Unit, Virology Service, Centre Pasteur of Cameroon, 451 Rue 2005. BP 1274, Yaounde, Cameroon. njouom@pasteur-yaounde.org.
Arch Virol ; 167(5): 1301-1305, 2022 May.
Article em En | MEDLINE | ID: mdl-35348916
ABSTRACT
We sequenced a portion of the E1 envelope protein gene of two of four CHIKV RT-PCR-positive samples from the first cluster of chikungunya patients during the 2020 Chad outbreak. Phylogenetic analysis revealed that the viruses belonged to the East/Central/South/African genotype but lacked the E1 A226V and K211E mutations associated with viral adaptability and transmission, suggesting an autochthonous transmission. These sequences are a useful basis for tracking viral evolution in subsequent outbreaks in Chad.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Humans País/Região como assunto: Africa Idioma: En Revista: Arch Virol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Camarões
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Humans País/Região como assunto: Africa Idioma: En Revista: Arch Virol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Camarões