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Reducing Nav1.6 expression attenuates the pathogenesis of Alzheimer's disease by suppressing BACE1 transcription.
Yuan, De-Juan; Yang, Guang; Wu, Wei; Li, Qi-Fa; Xu, De-En; Ntim, Michael; Jiang, Chun-Yan; Liu, Ji-Chuan; Zhang, Yue; Wang, Ying-Zi; Zhu, Dan-Dan; Kundu, Supratik; Li, Ai-Ping; Xiao, Zhi-Cheng; Ma, Quan-Hong; Li, Shao.
Afiliação
  • Yuan DJ; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Yang G; Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Wu W; Jiangsu Key Laboratory of Neuropsychiatric Diseases, Institute of Neuroscience, Soochow University, Suzhou, China.
  • Li QF; The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, China.
  • Xu DE; Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Ntim M; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Jiang CY; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Liu JC; Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Zhang Y; Jiangsu Key Laboratory of Neuropsychiatric Diseases, Institute of Neuroscience, Soochow University, Suzhou, China.
  • Wang YZ; The Affiliated Wuxi No. 2 People's Hospital of Nanjing Medical University, Wuxi, China.
  • Zhu DD; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Kundu S; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Li AP; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Xiao ZC; Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Ma QH; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
  • Li S; Department of Physiology, College of Basic Medical Sciences, Liaoning Provincial Key Laboratory of Cerebral Diseases, National-Local Joint Engineering Research Center for Drug-Research and Development (R&D) of Neurodegenerative Diseases, Dalian Medical University, Dalian, China.
Aging Cell ; 21(5): e13593, 2022 05.
Article em En | MEDLINE | ID: mdl-35353937
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Canal de Sódio Disparado por Voltagem NAV1.6 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Aging Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Secretases da Proteína Precursora do Amiloide / Doença de Alzheimer / Canal de Sódio Disparado por Voltagem NAV1.6 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Aging Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China