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Monogenic and Polygenic Contributions to QTc Prolongation in the Population.
Nauffal, Victor; Morrill, Valerie N; Jurgens, Sean J; Choi, Seung Hoan; Hall, Amelia W; Weng, Lu-Chen; Halford, Jennifer L; Austin-Tse, Christina; Haggerty, Christopher M; Harris, Stephanie L; Wong, Eugene K; Alonso, Alvaro; Arking, Dan E; Benjamin, Emelia J; Boerwinkle, Eric; Min, Yuan-I; Correa, Adolfo; Fornwalt, Brandon K; Heckbert, Susan R; Kooperberg, Charles; Lin, Henry J; J F Loos, Ruth; Rice, Kenneth M; Gupta, Namrata; Blackwell, Thomas W; Mitchell, Braxton D; Morrison, Alanna C; Psaty, Bruce M; Post, Wendy S; Redline, Susan; Rehm, Heidi L; Rich, Stephen S; Rotter, Jerome I; Soliman, Elsayed Z; Sotoodehnia, Nona; Lunetta, Kathryn L; Ellinor, Patrick T; Lubitz, Steven A.
Afiliação
  • Nauffal V; Division of Cardiovascular Medicine (V.N.), Brigham and Women's Hospital, Boston, MA.
  • Morrill VN; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Jurgens SJ; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Choi SH; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Hall AW; Department of Experimental Cardiology, Amsterdam University Medical Centers, The Netherlands (S.J.J.).
  • Weng LC; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Halford JL; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Austin-Tse C; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Haggerty CM; Gene Regulation Observatory (A.W.H.), Broad Institute, Cambridge, MA.
  • Harris SL; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Wong EK; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Alonso A; Cardiovascular Disease Initiative (V.N., V.N.M., S.J.J., S.H.C., L.-C.W., J.L.H., P.T.E., S.A.L.), Broad Institute, Cambridge, MA.
  • Arking DE; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Benjamin EJ; Center for Genomic Medicine (C.A.-T., H.L.R.), Massachusetts General Hospital, Boston.
  • Boerwinkle E; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Min YI; Department of Translational Data Science and Informatics, Geisinger, Danville, PA (C.M.H., B.K.F.).
  • Correa A; Cardiovascular Genetics Program (S.L.H., E.K.W.), Massachusetts General Hospital, Boston.
  • Fornwalt BK; Cardiovascular Genetics Program (S.L.H., E.K.W.), Massachusetts General Hospital, Boston.
  • Heckbert SR; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).
  • Kooperberg C; Boston University School of Public Health, MA (E.J.B., K.L.L.).
  • Lin HJ; Boston University School of Medicine, MA (E.J.B.).
  • J F Loos R; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (E.B., A.C.M.).
  • Rice KM; Department of Medicine, University of Mississippi Medical Center, Jackson (Y.-I.M., A.C.).
  • Gupta N; Department of Medicine, University of Mississippi Medical Center, Jackson (Y.-I.M., A.C.).
  • Blackwell TW; Department of Translational Data Science and Informatics, Geisinger, Danville, PA (C.M.H., B.K.F.).
  • Mitchell BD; Cardiovascular Health Research Unit and Department of Epidemiology (S.R.H.).
  • Psaty BM; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA (C.K.).
  • Post WS; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-University of California-Los Angeles Medical Center, Torrance (H.J.L., J.I.R.).
  • Redline S; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York (R.J.F.L.).
  • Rehm HL; Department of Biostatistics (K.M.R.).
  • Rich SS; Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge (N.G., S.J.J., S.H.C., L.C.W., J.L.H., C.A.T., H.L.R., P.T.E., S.A.L.).
  • Rotter JI; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor (T.W.B.).
  • Soliman EZ; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore (B.D.M.).
  • Sotoodehnia N; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston (E.B., A.C.M.).
  • Lunetta KL; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Systems and Population Health, University of Washington, Seattle, WA (B.M.P.).
  • Ellinor PT; Division of Cardiology, Department of Medicine (W.S.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
  • Lubitz SA; Harvard Medical School (S.R.), Brigham and Women's Hospital, Boston, MA.
Circulation ; 145(20): 1524-1533, 2022 05 17.
Article em En | MEDLINE | ID: mdl-35389749

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Estudo de Associação Genômica Ampla Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Circulation Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Marrocos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Estudo de Associação Genômica Ampla Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Circulation Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Marrocos