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Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport.
Conze, Christian; Rierola, Marina; Trushina, Nataliya I; Peters, Michael; Janning, Dennis; Holzer, Max; Heinisch, Jürgen J; Arendt, Thomas; Bakota, Lidia; Brandt, Roland.
Afiliação
  • Conze C; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
  • Rierola M; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
  • Trushina NI; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
  • Peters M; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
  • Janning D; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
  • Holzer M; Center for Cellular Nanoanalytics, Osnabrück University, Osnabrück, Germany.
  • Heinisch JJ; Center for Neuropathology and Brain Research, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany.
  • Arendt T; Department of Genetics, Osnabrück University, Osnabrück, Germany.
  • Bakota L; Center for Neuropathology and Brain Research, Paul Flechsig Institute of Brain Research, University of Leipzig, Leipzig, Germany.
  • Brandt R; Department of Neurobiology, Osnabrück University, Osnabrück, Germany.
Mol Psychiatry ; 27(7): 3010-3023, 2022 07.
Article em En | MEDLINE | ID: mdl-35393558
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tauopatias / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tauopatias / Doença de Alzheimer Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Mol Psychiatry Assunto da revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha