Characterization of skeletal muscle wasting pathways in diaphragm and limb muscles of cystic fibrosis mice.

Gusev, Ekaterina; Liang, Feng; Bhattarai, Salyan; Broering, Felipe E; Leduc-Gaudet, Jean-Philippe; Hussain, Sabah N; Radzioch, Danuta; Petrof, Basil J

Gusev, Ekaterina; Liang, Feng; Bhattarai, Salyan; Broering, Felipe E; Leduc-Gaudet, Jean-Philippe; Hussain, Sabah N; Radzioch, Danuta; Petrof, Basil J.

Afiliação

Gusev E; Meakins-Christie Laboratories, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Liang F; Translational Research in Respiratory Diseases Program, McGill University Health Center and Research Institute, Montreal, Quebec, Canada.
Bhattarai S; Meakins-Christie Laboratories, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Broering FE; Translational Research in Respiratory Diseases Program, McGill University Health Center and Research Institute, Montreal, Quebec, Canada.
Leduc-Gaudet JP; Meakins-Christie Laboratories, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Hussain SN; Translational Research in Respiratory Diseases Program, McGill University Health Center and Research Institute, Montreal, Quebec, Canada.
Radzioch D; Meakins-Christie Laboratories, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Petrof BJ; Translational Research in Respiratory Diseases Program, McGill University Health Center and Research Institute, Montreal, Quebec, Canada.

Am J Physiol Regul Integr Comp Physiol ; 322(6): R551-R561, 2022 06 01.

Article em En | MEDLINE | ID: mdl-35411814

Assuntos

Fibrose Cística; Diafragma; Animais; Calpaína/metabolismo; Fibrose Cística/genética; Fibrose Cística/metabolismo; Fibrose Cística/patologia; Regulador de Condutância Transmembrana em Fibrose Cística/metabolismo; Citocinas/metabolismo; Humanos; Inflamação/metabolismo; Lipopolissacarídeos; Camundongos; Músculo Esquelético/metabolismo; Atrofia Muscular/metabolismo; Complexo de Endopeptidases do Proteassoma/metabolismo; Ubiquitinas/metabolismo

Palavras-chave

CFTR; atrophy; cachexia; inflammatory cytokines; proteolysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diafragma / Fibrose Cística Limite: Animals / Humans Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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