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Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis.
Asif, Shaza; Kim, Ri Youn; Fatica, Thet; Sim, Jordan; Zhao, Xiaoling; Oh, Yena; Denoncourt, Alix; Cheung, Angela C; Downey, Michael; Mulvihill, Erin E; Kim, Kyoung-Han.
Afiliação
  • Asif S; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.
  • Kim RY; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada.
  • Fatica T; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada.
  • Sim J; Department of Pathology and Laboratory Medicine, The Ottawa Hospital, Ottawa, ON, K1H 8M5, Canada.
  • Zhao X; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada.
  • Oh Y; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.
  • Denoncourt A; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada; Ottawa Institute of Systems Biology, Ottawa, ON, K1H 8M5, Canada.
  • Cheung AC; Gastroenterology and Hepatology, Department of Medicine, The Ottawa Hospital, Ottawa, ON, K1H 8M5, Canada; The Ottawa Hospital Research Institute, Chronic Disease Program, Ottawa, ON, K1Y 4E9, Canada.
  • Downey M; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada; Ottawa Institute of Systems Biology, Ottawa, ON, K1H 8M5, Canada.
  • Mulvihill EE; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.
  • Kim KH; University of Ottawa Heart Institute, Ottawa, ON, K1Y 4W7, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada. Electronic address: hkim@ottawaheart.ca.
Mol Metab ; 61: 101494, 2022 07.
Article em En | MEDLINE | ID: mdl-35421611
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Hiperlipídica / Hepatopatia Gordurosa não Alcoólica / Hidroximetilglutaril-CoA Sintase / Cetose Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Mol Metab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dieta Hiperlipídica / Hepatopatia Gordurosa não Alcoólica / Hidroximetilglutaril-CoA Sintase / Cetose Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Revista: Mol Metab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá