Progressive Reduction in Right Ventricular Contractile Function Attributable to Altered Actin Expression in an Aging Mouse Model of Arrhythmogenic Cardiomyopathy.

Camors, Emmanuel M; Roth, Alyson H; Alef, Joseph R; Sullivan, Ryan D; Johnson, Jason N; Purevjav, Enkhsaikhan; Towbin, Jeffrey A

Camors, Emmanuel M; Roth, Alyson H; Alef, Joseph R; Sullivan, Ryan D; Johnson, Jason N; Purevjav, Enkhsaikhan; Towbin, Jeffrey A.

Afiliação

Camors EM; Heart Institute, Department of Pediatrics, University of Tennessee Health Science Center, Memphis (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Roth AH; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Alef JR; Heart Institute, Department of Pediatrics, University of Tennessee Health Science Center, Memphis (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Sullivan RD; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Johnson JN; Heart Institute, Department of Pediatrics, University of Tennessee Health Science Center, Memphis (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Purevjav E; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN (E.M.C., A.H.R., J.R.A., J.N.J., E.P., J.A.T.).
Towbin JA; Department of Internal Medicine, University of Arizona College of Medicine, Phoenix (R.D.S.).

Circulation ; 145(21): 1609-1624, 2022 05 24.

Article em En | MEDLINE | ID: mdl-35437032

Assuntos

Displasia Arritmogênica Ventricular Direita; Cardiomiopatias; Actinas; Envelhecimento; Animais; Displasia Arritmogênica Ventricular Direita/patologia; Cardiomiopatias/genética; Morte Súbita Cardíaca; Modelos Animais de Doenças; Humanos; Camundongos; Placofilinas/genética; Troponina I

Palavras-chave

aging; arrhythmogenic right ventricular dysplasia; plakophilins; sarcomeres

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Displasia Arritmogênica Ventricular Direita / Cardiomiopatias Limite: Animals / Humans Idioma: En Revista: Circulation Ano de publicação: 2022 Tipo de documento: Article

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