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Cell-Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR-ABL Kinase.
Chen, Peng; Sun, Jie; Zhu, Chengjun; Tang, Guanghui; Wang, Wei; Xu, Manyi; Xiang, Menghua; Zhang, Chong-Jing; Zhang, Zhi-Min; Gao, Liqian; Yao, Shao Q.
Afiliação
  • Chen P; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
  • Sun J; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
  • Zhu C; School of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, 510632, China.
  • Tang G; Guangdong Youmei Institute of Intelligent Bio-manufacturing Foshan, Guangdong, 528200, China.
  • Wang W; Department of Chemistry, National University of Singapore, Singapore, 117543, Singapore.
  • Xu M; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
  • Xiang M; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines and Beijing Key Laboratory of Active Substances Discovery and, Drugability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Zhang CJ; School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
  • Zhang ZM; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines and Beijing Key Laboratory of Active Substances Discovery and, Drugability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Gao L; School of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou, 510632, China.
  • Yao SQ; Guangdong Youmei Institute of Intelligent Bio-manufacturing Foshan, Guangdong, 528200, China.
Angew Chem Int Ed Engl ; 61(26): e202203878, 2022 06 27.
Article em En | MEDLINE | ID: mdl-35438229
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China