Cytotoxicity of Thioalkaloid-Enriched <i>Nuphar lutea</i> Extract and Purified 6,6'-Dihydroxythiobinupharidine in Acute Myeloid Leukemia Cells: The Role of Oxidative Stress and Intracellular Calcium.

Muduli, Suchismita; Golan-Goldhirsh, Avi; Gopas, Jacob; Danilenko, Michael

Cytotoxicity of Thioalkaloid-Enriched Nuphar lutea Extract and Purified 6,6'-Dihydroxythiobinupharidine in Acute Myeloid Leukemia Cells: The Role of Oxidative Stress and Intracellular Calcium.

Muduli, Suchismita; Golan-Goldhirsh, Avi; Gopas, Jacob; Danilenko, Michael.

Afiliação

Muduli S; Department of Clinical Biochemistry & Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Golan-Goldhirsh A; The Jacob Blaustein Institutes for Desert Research (BIDR), French Associates Institute for Agriculture and Biotechnology of Drylands, Ben-Gurion University of the Negev, Sede Boqer Campus, Midreshet Ben Gurion 8499000, Israel.
Gopas J; Department of Microbiology, Immunology & Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Danilenko M; Department of Oncology, Soroka University Medical Center, Beer Sheva 8410101, Israel.

Pharmaceuticals (Basel) ; 15(4)2022 Mar 28.

Article em En | MEDLINE | ID: mdl-35455407

Palavras-chave

6,6'-dihydroxythiobinupharidine (DTBN); acute myeloid leukemia (AML); apoptosis; intracellular calcium; oxidative stress; reactive oxygen species (ROS); water lily (Nuphar lutea) extract (NUP)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Israel

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