InsuLock: A Weakly Supervised Learning Approach for Accurate Insulator Prediction, and Variant Impact Quantification.

Srinivasan, Shushrruth Sai; Gong, Yanwen; Xu, Siwei; Hwang, Ahyeon; Xu, Min; Girgenti, Matthew J; Zhang, Jing

Srinivasan, Shushrruth Sai; Gong, Yanwen; Xu, Siwei; Hwang, Ahyeon; Xu, Min; Girgenti, Matthew J; Zhang, Jing.

Afiliação

Srinivasan SS; Computer Science Department, University of California, Irvine, CA 92697, USA.
Gong Y; Mathematical, Computational & Systems Biology, University of California, Irvine, CA 92697, USA.
Xu S; Computer Science Department, University of California, Irvine, CA 92697, USA.
Hwang A; Mathematical, Computational & Systems Biology, University of California, Irvine, CA 92697, USA.
Xu M; Computational Biology Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
Girgenti MJ; Department of Psychiatry, School of Medicine, Yale University, New Haven, CT 06520, USA.
Zhang J; Computer Science Department, University of California, Irvine, CA 92697, USA.

Genes (Basel) ; 13(4)2022 03 30.

Article em En | MEDLINE | ID: mdl-35456427

Assuntos

Cromatina; Redes Neurais de Computação; Fator de Ligação a CCCTC/genética; Genoma; Aprendizado de Máquina Supervisionado

Palavras-chave

3D chromatin structure; CTCF mediated insulator loops; brain disorders; deep learning; gene regulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Redes Neurais de Computação Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Genes (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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