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Structural insight into SSE15206 in complex with tubulin provides a rational design for pyrazolinethioamides as tubulin polymerization inhibitors.
Ma, Lingling; Lei, Jiahong; Chen, Hai; Huang, Ridong; Su, Tao; Feng, Jianrong; Sun, Qiu.
Afiliação
  • Ma L; Department of Respiratory & Critical Care Medicine, Targeted Tracer Research & development laboratory, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Lei J; Cancer Center, West China Hospital, Sichuan University & Collaborative Innovation Center of Biotherapy, Chengdu, 610041, China.
  • Chen H; Biomedical research center, Affiliated Hospital of North Sichuan Medical College, Nanchong, China. Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, P.R. China.North Sichuan Medical College, Nanchong, China.
  • Huang R; Department of Respiratory & Critical Care Medicine, Targeted Tracer Research & development laboratory, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Su T; Department of Respiratory & Critical Care Medicine, Targeted Tracer Research & development laboratory, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Feng J; Laboratory of Clinical Proteomics & Metabolomics, Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, 88 Keyuan South Road, Hi-Tech Zone, Chengdu, 610041, China
  • Sun Q; Department of Nuclear Medicine, Nuclear Medicine & Molecular Imaging Key Laboratory of Sichuan Province, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Future Med Chem ; 14(11): 785-794, 2022 06.
Article em En | MEDLINE | ID: mdl-35506429
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Moduladores de Tubulina / Antineoplásicos Idioma: En Revista: Future Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Moduladores de Tubulina / Antineoplásicos Idioma: En Revista: Future Med Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China