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Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL.
Edmonds, Anthony K; Oakes, Catherine S; Hassell-Hart, Storm; Bruyère, Didier; Tizzard, Graham J; Coles, Simon J; Felix, Robert; Maple, Hannah J; Marsh, Graham P; Spencer, John.
Afiliação
  • Edmonds AK; Chemistry Department, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK. j.spencer@sussex.ac.uk.
  • Oakes CS; Bio-Techne (Tocris), The Watkins Building, Atlantic Road, Bristol, BS11 9QD, UK.
  • Hassell-Hart S; Chemistry Department, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK. j.spencer@sussex.ac.uk.
  • Bruyère D; Bio-Techne (Tocris), The Watkins Building, Atlantic Road, Bristol, BS11 9QD, UK.
  • Tizzard GJ; National Crystallography Service, School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.
  • Coles SJ; National Crystallography Service, School of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.
  • Felix R; Bio-Techne (Tocris), The Watkins Building, Atlantic Road, Bristol, BS11 9QD, UK.
  • Maple HJ; Bio-Techne (Tocris), The Watkins Building, Atlantic Road, Bristol, BS11 9QD, UK.
  • Marsh GP; Bio-Techne (Tocris), The Watkins Building, Atlantic Road, Bristol, BS11 9QD, UK.
  • Spencer J; Chemistry Department, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK. j.spencer@sussex.ac.uk.
Org Biomol Chem ; 20(19): 4021-4029, 2022 05 18.
Article em En | MEDLINE | ID: mdl-35506991
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido