Chronic arsenic exposure suppresses ATM pathway activation in human keratinocytes.

Nail, Alexandra N; McCaffrey, Lakynkalina M; Banerjee, Mayukh; Ferragut Cardoso, Ana P; States, J Christopher

Nail, Alexandra N; McCaffrey, Lakynkalina M; Banerjee, Mayukh; Ferragut Cardoso, Ana P; States, J Christopher.

Afiliação

Nail AN; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Science, University of Louisville, Louisville, KY 40209, United States of America.
McCaffrey LM; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Science, University of Louisville, Louisville, KY 40209, United States of America.
Banerjee M; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Science, University of Louisville, Louisville, KY 40209, United States of America.
Ferragut Cardoso AP; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Science, University of Louisville, Louisville, KY 40209, United States of America.
States JC; Department of Pharmacology and Toxicology, Center for Integrative Environmental Health Science, University of Louisville, Louisville, KY 40209, United States of America. Electronic address: jcstates@louisville.edu.

Toxicol Appl Pharmacol ; 446: 116042, 2022 07 01.

Article em En | MEDLINE | ID: mdl-35513056

Assuntos

Arsênio; Proteínas Mutadas de Ataxia Telangiectasia; Queratinócitos; Arsênio/metabolismo; Arsênio/toxicidade; Ataxia; Proteínas Mutadas de Ataxia Telangiectasia/genética; Proteínas Mutadas de Ataxia Telangiectasia/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Reparo do DNA; Proteínas de Ligação a DNA/genética; Transição Epitelial-Mesenquimal; Humanos; Queratinócitos/metabolismo; Proteína Homóloga a MRE11/genética; Proteína Homóloga a MRE11/metabolismo

Palavras-chave

ATM; Arsenic; DNA damage response; Keratinocytes; MRN; Phosphatases

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arsênio / Queratinócitos / Proteínas Mutadas de Ataxia Telangiectasia Limite: Humans Idioma: En Revista: Toxicol Appl Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google