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Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model.
Chin, Marcus Y; Ang, Kean-Hooi; Davies, Julia; Alquezar, Carolina; Garda, Virginia G; Rooney, Brendan; Leng, Kun; Kampmann, Martin; Arkin, Michelle R; Kao, Aimee W.
Afiliação
  • Chin MY; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California, California 94158, United States.
  • Ang KH; Small Molecule Discovery Center, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States.
  • Davies J; Small Molecule Discovery Center, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States.
  • Alquezar C; Small Molecule Discovery Center, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States.
  • Garda VG; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California, California 94158, United States.
  • Rooney B; Memory and Aging Center, Department of Neurology, University of California, San Francisco, California, California 94158, United States.
  • Leng K; Small Molecule Discovery Center, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143, United States.
  • Kampmann M; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, United States.
  • Arkin MR; Institute for Neurodegenerative Diseases, Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, United States.
  • Kao AW; Biomedical Sciences Graduate Program, University of California, San Francisco, California 94158, United States.
ACS Chem Neurosci ; 13(10): 1505-1516, 2022 05 18.
Article em En | MEDLINE | ID: mdl-35522480
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Lisossomos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Neurodegenerativas / Lisossomos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: ACS Chem Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos