TripletGO: Integrating Transcript Expression Profiles with Protein Homology Inferences for Gene Function Prediction.

Zhu, Yi-Heng; Zhang, Chengxin; Liu, Yan; Omenn, Gilbert S; Freddolino, Peter L; Yu, Dong-Jun; Zhang, Yang

Zhu, Yi-Heng; Zhang, Chengxin; Liu, Yan; Omenn, Gilbert S; Freddolino, Peter L; Yu, Dong-Jun; Zhang, Yang.

Afiliação

Zhu YH; School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Zhang C; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
Liu Y; School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
Omenn GS; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Departments of Internal Medicine and Human Genetics, and School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA.
Freddolino PL; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Yu DJ; School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China. Electronic address: njyudj@njust.edu.cn.
Zhang Y; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: zhang@zhanggroup.org.

Genomics Proteomics Bioinformatics ; 20(5): 1013-1027, 2022 10.

Article em En | MEDLINE | ID: mdl-35568117

Assuntos

Biologia Computacional; Proteínas; Animais; Camundongos; Ratos; Humanos; Proteínas/metabolismo; Anotação de Sequência Molecular; Sequência de Aminoácidos; Alinhamento de Sequência; Biologia Computacional/métodos

Palavras-chave

Gene Ontology; Gene function annotation; Protein-level alignment; Transcript expression profile; Triplet network

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Biologia Computacional Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Genomics Proteomics Bioinformatics Assunto da revista: BIOQUIMICA / GENETICA / INFORMATICA MEDICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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