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Rational design of chimeric antigen receptor T cells against glypican 3 decouples toxicity from therapeutic efficacy.
Giardino Torchia, Maria Letizia; Gilbreth, Ryan; Merlino, Ashley; Sult, Erin; Monks, Noel; Chesebrough, Jon; Tammali, Ravinder; Chu, Nina; Tong, Jessica; Meekin, John; Schifferli, Kevin; Vashisht, Kapil; DaCosta, Karma; Clarke, Lori; Gesse, Christina; Yao, Xiao-Tao; Bridges, Courtney; Moody, Gordon.
Afiliação
  • Giardino Torchia ML; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Gilbreth R; Antibody Discovery and Protein Engineering, AstraZeneca PLC Gaithersburg, MD.
  • Merlino A; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Sult E; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Monks N; Oncology Research, AstraZeneca PLC Gaithersburg, MD; NeuBase Therapeutics, INC Pittsburgh, PA.
  • Chesebrough J; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Tammali R; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Chu N; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Tong J; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Meekin J; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Schifferli K; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Vashisht K; Oncology Pathology, AstraZeneca PLC Gaithersburg, MD.
  • DaCosta K; Oncology Pathology, AstraZeneca PLC Gaithersburg, MD.
  • Clarke L; Antibody Discovery and Protein Engineering, AstraZeneca PLC Gaithersburg, MD.
  • Gesse C; Antibody Discovery and Protein Engineering, AstraZeneca PLC Gaithersburg, MD.
  • Yao XT; Antibody Discovery and Protein Engineering, AstraZeneca PLC Gaithersburg, MD.
  • Bridges C; Oncology Research, AstraZeneca PLC Gaithersburg, MD.
  • Moody G; Oncology Research, AstraZeneca PLC Gaithersburg, MD. Electronic address: gordon.moody@astrazeneca.com.
Cytotherapy ; 24(7): 720-732, 2022 07.
Article em En | MEDLINE | ID: mdl-35570170
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glipicanas / Receptores de Antígenos Quiméricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cytotherapy Assunto da revista: TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Moldávia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glipicanas / Receptores de Antígenos Quiméricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cytotherapy Assunto da revista: TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Moldávia