Nanocapsules Produced by Nanoprecipitation of Designed Suckerin-Silk Fusion Proteins.
ACS Macro Lett
; 10(5): 628-634, 2021 05 18.
Article
em En
| MEDLINE
| ID: mdl-35570771
ABSTRACT
Herein, we report on the precise design of a modular fusion protein amenable to the construction of nanocapsules by nanoprecipitation. The central squid suckerin-derived peptide block provides structural stability, whereas both termini from spider silk fibroins make the protein highly soluble at physiological pH, a critical requirement for the nanoprecipitation process. With this design, nanocapsules consisting of fusion protein shells and oily cores with sizes in the range of 190-250 nm are built in a straightforward manner.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nanocápsulas
/
Fibroínas
Limite:
Animals
Idioma:
En
Revista:
ACS Macro Lett
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
França