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Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection.
Zhang, Chao; Verma, Anurag; Feng, Yuanqing; Melo, Marcelo C R; McQuillan, Michael; Hansen, Matthew; Lucas, Anastasia; Park, Joseph; Ranciaro, Alessia; Thompson, Simon; Rubel, Meagan A; Campbell, Michael C; Beggs, William; Hirbo, Jibril; Wata Mpoloka, Sununguko; George Mokone, Gaonyadiwe; Nyambo, Thomas; Wolde Meskel, Dawit; Belay, Gurja; Fokunang, Charles; Njamnshi, Alfred K; Omar, Sabah A; Williams, Scott M; Rader, Daniel J; Ritchie, Marylyn D; de la Fuente-Nunez, Cesar; Sirugo, Giorgio; Tishkoff, Sarah A.
Afiliação
  • Zhang C; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Verma A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Feng Y; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104.
  • Melo MCR; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • McQuillan M; Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Hansen M; Departments of Bioengineering and Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104.
  • Lucas A; Penn Institute for Computational Science, University of Pennsylvania, Philadelphia, PA 19104.
  • Park J; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Ranciaro A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Thompson S; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Rubel MA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Campbell MC; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Beggs W; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Hirbo J; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Wata Mpoloka S; Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089.
  • George Mokone G; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Nyambo T; Biological Sciences, University of Botswana, Gaborone, Botswana.
  • Wolde Meskel D; Faculty of Medicine, University of Botswana, Gaborone, Botswana.
  • Belay G; Regeneron Genetics Center, Tarrytown, NY 10591.
  • Fokunang C; Department of Biochemistry, Kampala International University in Tanzania, Dar es Salaam, Tanzania.
  • Njamnshi AK; Department of Microbial Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia.
  • Omar SA; Department of Microbial Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, Ethiopia.
  • Williams SM; Department of Pharmacotoxicology and Pharmacokinetics, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
  • Rader DJ; Department of Neurology, Central Hospital Yaoundé, Yaoundé, Cameroon.
  • Ritchie MD; Brain Research Africa Initiative, Neuroscience Laboratory, Faculty of Medicine and Biomedical Sciences, The University of Yaoundé I, Yaoundé, Cameroon.
  • de la Fuente-Nunez C; Center for Biotechnology Research and Development, Kenya Medical Research Institute, Nairobi, Kenya.
  • Sirugo G; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106.
  • Tishkoff SA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 119(21): e2123000119, 2022 05 24.
Article em En | MEDLINE | ID: mdl-35580180

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Risk_factors_studies Limite: Humans País/Região como assunto: Africa Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 Tipo de estudo: Risk_factors_studies Limite: Humans País/Região como assunto: Africa Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article