Ketotherapy: Cutting carbs to treat cancer.

Radyk, Megan D; Kerk, Samuel A; Lyssiotis, Costas A

Radyk, Megan D; Kerk, Samuel A; Lyssiotis, Costas A.

Afiliação

Radyk MD; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA.
Kerk SA; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA; Doctoral Program in Cancer Biology, University of Michigan, Ann Arbor, MI, USA.
Lyssiotis CA; Doctoral Program in Cancer Biology, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. Electronic address: clyssiot@med.umich.edu.

Med ; 3(2): 87-89, 2022 02 11.

Article em En | MEDLINE | ID: mdl-35590211

ABSTRACT

ABSTRACT

Dietary interventions hold promise in cancer treatments. However, clinical application has been limited by a lack of mechanistic understanding of the metabolic effects. In this issue, Yang et al. use mouse models and isotope tracing to demonstrate that the ketogenic diet induces reductive stress and primes pancreatic tumors for chemotherapy.1.

Assuntos

Dieta Cetogênica; Neoplasias Pancreáticas; Animais; Carboidratos; Modelos Animais de Doenças; Camundongos; Neoplasias Pancreáticas/tratamento farmacológico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Dieta Cetogênica Limite: Animals Idioma: En Revista: Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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