Tumor microenvironment-responsive versatile "Trojan horse" theranostic nanoplatform for magnetic resonance imaging-guided multimodal synergistic antitumor treatment.

Huang, Qingli; Pan, Yuanjie; Wang, Meng; Liu, Zhaorong; Chen, Huimin; Wang, Jinglei; Zhao, Ziming; Zhang, Yanzhuo

Huang, Qingli; Pan, Yuanjie; Wang, Meng; Liu, Zhaorong; Chen, Huimin; Wang, Jinglei; Zhao, Ziming; Zhang, Yanzhuo.

Afiliação

Huang Q; Public experimental research center of Xuzhou Medical University, Xuzhou, 221004, China.
Pan Y; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
Wang M; Public experimental research center of Xuzhou Medical University, Xuzhou, 221004, China.
Liu Z; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
Chen H; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
Wang J; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China.
Zhao Z; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, PR China. Electronic address: zmzhao@xzhmu.edu.cn.
Zhang Y; School of Pharmacy, Xuzhou Medical University, Xuzhou, 221004, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, 221004, PR China. Electronic address: yanzhuozhang@xzhmu.edu.cn.

Acta Biomater ; 147: 270-286, 2022 07 15.

Article em En | MEDLINE | ID: mdl-35595202

Assuntos

Nanopartículas; Neoplasias; Animais; Doxorrubicina/química; Doxorrubicina/farmacologia; Doxorrubicina/uso terapêutico; Imageamento por Ressonância Magnética; Compostos de Manganês/química; Compostos de Manganês/farmacologia; Proteínas de Membrana/farmacologia; Camundongos; Camundongos Nus; Nanopartículas/química; Neoplasias/diagnóstico por imagem; Neoplasias/tratamento farmacológico; Óxidos/química; Medicina de Precisão; Nanomedicina Teranóstica; Microambiente Tumoral

Palavras-chave

Synergistic treatment; Targeting delivery; Theranostic nanoplatform; Tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanopartículas / Neoplasias Limite: Animals Idioma: En Revista: Acta Biomater Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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