Brain uptake and distribution patterns of 2-hydroxypropyl-ß-cyclodextrin after intrathecal and intranasal administration.

Banks, William A; Calias, Pericles; Hansen, Kim M; Bullock, Kristin M; Engelke, Kory

Banks, William A; Calias, Pericles; Hansen, Kim M; Bullock, Kristin M; Engelke, Kory.

Afiliação

Banks WA; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Calias P; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Hansen KM; Educational Trainers and Consultants, Melrose, MA, USA.
Bullock KM; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Engelke K; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

J Pharm Pharmacol ; 74(8): 1152-1159, 2022 Aug 19.

Article em En | MEDLINE | ID: mdl-35596793

Assuntos

Ciclodextrinas; Doenças de Niemann-Pick; Administração Intranasal; Barreira Hematoencefálica; Encéfalo; Humanos; Derivados da Hipromelose

Palavras-chave

bloodbrain barrier; central; cyclodextrin; intranasal; intrathecal

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças de Niemann-Pick / Ciclodextrinas Limite: Humans Idioma: En Revista: J Pharm Pharmacol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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