Mutations in DNA binding domain of p53 impede RSL1D1-p53 interaction to escape from degradation in human colorectal cancer cells.

Ding, Li; Zhao, Chenhong; Xu, Yujie; Zhang, Zhiping; Nie, Yesen; Liao, Kai; Chen, Yuerou; Tu, Beibei; Zhang, Xinyue

Ding, Li; Zhao, Chenhong; Xu, Yujie; Zhang, Zhiping; Nie, Yesen; Liao, Kai; Chen, Yuerou; Tu, Beibei; Zhang, Xinyue.

Afiliação

Ding L; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Zhao C; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Xu Y; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Zhang Z; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Nie Y; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Liao K; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Chen Y; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Tu B; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China.
Zhang X; College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, Jiangsu, 225009, China; Joint International Research Laboratory of Agriculture & Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, Jiangsu, 225009, China; Key Laboratory of Prevention an

Exp Cell Res ; 417(1): 113211, 2022 08 01.

Article em En | MEDLINE | ID: mdl-35597299

Assuntos

Neoplasias Colorretais; Proteínas da Gravidez; Proteínas Ribossômicas; Proteína Supressora de Tumor p53; Linhagem Celular Tumoral; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; DNA; Células HCT116; Humanos; Proteínas Mutantes/metabolismo; Mutação/genética; Proteínas da Gravidez/química; Proteínas da Gravidez/metabolismo; Proteínas Ribossômicas/genética; Proteínas Ribossômicas/metabolismo; Proteína Supressora de Tumor p53/química; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

Colorectal cancer cells; DNA binding Domain; Mutant p53; Protein-protein interaction; R175H; R273H; RSL1D1; Truncated variants

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas da Gravidez / Proteínas Ribossômicas / Neoplasias Colorretais / Proteína Supressora de Tumor p53 Limite: Humans Idioma: En Revista: Exp Cell Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google