Propargyl Chalcones' Radical Annulation/Sulfonation Reaction: Efficient Synthesis of Benzo[b]oxepin-5(2H)-one and Chromane Derivatives.
J Org Chem
; 87(11): 7136-7149, 2022 06 03.
Article
em En
| MEDLINE
| ID: mdl-35607936
ABSTRACT
A novel and facile methodology for the synthesis of sulfonated benzo[b]oxepinone and chromane derivatives was reported by the reaction of propargyl chalcones with arylsulfonyl chloride via radical cascade annulation/sulfonation under laboratory conditions. Readily available propargyl chalcones, commercialized arylsulfonyl chloride, and simple reaction conditions make this six(seven)-membered oxygen-containing heterocycles' synthetic strategy more attractive and with significant application values.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Chalconas
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2022
Tipo de documento:
Article