NLRP3/Caspase-1-Mediated Pyroptosis of Astrocytes Induced by Antipsychotics Is Inhibited by a Histamine H1 Receptor-Selective Agonist.

He, Meng; Fan, Jun; Zhou, Ruqin; Gao, Guanbin; Li, Ruoxi; Zuo, YuFeng; Li, Benben; Li, Yanmei; Sun, Taolei

He, Meng; Fan, Jun; Zhou, Ruqin; Gao, Guanbin; Li, Ruoxi; Zuo, YuFeng; Li, Benben; Li, Yanmei; Sun, Taolei.

Afiliação

He M; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.
Fan J; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.
Zhou R; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.
Gao G; State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, China.
Li R; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zuo Y; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.
Li B; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.
Li Y; Hubei Provincial Key Laboratory for Applied Toxicology, Hubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Sun T; School of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan, China.

Front Aging Neurosci ; 14: 847561, 2022.

Article em En | MEDLINE | ID: mdl-35615587

Palavras-chave

GSDMD; NLRP3; antipsychotics; astrocytes; brain volume loss; caspase-1; pyroptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Aging Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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