Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma.

Mi, Haoyang; Ho, Won Jin; Yarchoan, Mark; Popel, Aleksander S

Mi, Haoyang; Ho, Won Jin; Yarchoan, Mark; Popel, Aleksander S.

Afiliação

Mi H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Ho WJ; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Yarchoan M; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Popel AS; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Front Immunol ; 13: 892250, 2022.

Article em En | MEDLINE | ID: mdl-35634309

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; Anilidas; Antígeno B7-H1/metabolismo; Linfócitos T CD8-Positivos/metabolismo; Carcinoma Hepatocelular/patologia; Humanos; Neoplasias Hepáticas/patologia; Nivolumabe/uso terapêutico; Piridinas; Análise Espacial; Microambiente Tumoral; Fator A de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

biomarker; computational biology; hepatocellular carcinoma; immunotherapy; systems biology; tumor-immune microenvironments (TIME)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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