Targeted modifications of neomycin and paromomycin: Towards resistance-free antibiotics?

Obszynski, J; Loidon, H; Blanc, A; Weibel, J-M; Pale, P

Obszynski, J; Loidon, H; Blanc, A; Weibel, J-M; Pale, P.

Afiliação

Obszynski J; Institute of Chemistry, UMR 7177, CNRS and University of Strasbourg, 4 rue B. Pascal, 67000 Strasbourg, France.
Loidon H; Institute of Chemistry, UMR 7177, CNRS and University of Strasbourg, 4 rue B. Pascal, 67000 Strasbourg, France.
Blanc A; Institute of Chemistry, UMR 7177, CNRS and University of Strasbourg, 4 rue B. Pascal, 67000 Strasbourg, France.
Weibel JM; Institute of Chemistry, UMR 7177, CNRS and University of Strasbourg, 4 rue B. Pascal, 67000 Strasbourg, France. Electronic address: jmweibel@unistra.fr.
Pale P; Institute of Chemistry, UMR 7177, CNRS and University of Strasbourg, 4 rue B. Pascal, 67000 Strasbourg, France. Electronic address: ppale@unistra.fr.

Bioorg Chem ; 126: 105824, 2022 09.

Article em En | MEDLINE | ID: mdl-35636122

Assuntos

Infecções Bacterianas; Neomicina; Aminoglicosídeos/química; Aminoglicosídeos/farmacologia; Antibacterianos/química; Bactérias; Humanos; Neomicina/química; Neomicina/farmacologia; Paromomicina/química; Paromomicina/farmacologia

Palavras-chave

Antibiotics; Bacterial resistance; Chemical modifications; Neomycin; Paromomycin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Neomicina Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França

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