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A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines.
Phan, Thanh T N; Hvasta, Matthew G; Kudlacek, Stephan T; Thiono, Devina J; Tripathy, Ashutosh; Nicely, Nathan I; de Silva, Aravinda M; Kuhlman, Brian.
Afiliação
  • Phan TTN; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Hvasta MG; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Thiono DJ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Tripathy A; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Nicely NI; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • de Silva AM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address: bkuhlman@email.unc.edu.
J Biol Chem ; 298(7): 102079, 2022 07.
Article em En | MEDLINE | ID: mdl-35643320
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Proteínas do Envelope Viral / Vacinas de Subunidades Antigênicas / Vírus da Dengue / Zika virus Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Proteínas do Envelope Viral / Vacinas de Subunidades Antigênicas / Vírus da Dengue / Zika virus Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos