Bisphenol A Analogs Induce Cellular Dysfunction in Human Trophoblast Cells in a Thyroid Hormone Receptor-Dependent Manner: <i>In Silico</i> and <i>In Vitro</i> Analyses.

Wu, Xiaoyun; Yang, Xiaowen; Geng, Xilin; Ji, Xiaotong; Zhang, Xiaozheng; Yue, Huifeng; Li, Guangke; Sang, Nan

Bisphenol A Analogs Induce Cellular Dysfunction in Human Trophoblast Cells in a Thyroid Hormone Receptor-Dependent Manner: In Silico and In Vitro Analyses.

Wu, Xiaoyun; Yang, Xiaowen; Geng, Xilin; Ji, Xiaotong; Zhang, Xiaozheng; Yue, Huifeng; Li, Guangke; Sang, Nan.

Afiliação

Wu X; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.
Yang X; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.
Geng X; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.
Ji X; Department of Environmental Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi 030001, P. R. China.
Zhang X; Department of Biochemistry and Molecular Biology, Shanxi Key Laboratory of Birth Defect and Cell Regeneration, Shanxi Medical University, Taiyuan, Shanxi, 030001, P. R. China.
Yue H; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.
Li G; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.
Sang N; College of Environment and Resource, Research Center of Environment and Health, Shanxi University, Taiyuan, Shanxi 030006, P. R. China.

Environ Sci Technol ; 56(12): 8384-8394, 2022 06 21.

Article em En | MEDLINE | ID: mdl-35666658

Assuntos

Receptores dos Hormônios Tireóideos; Trofoblastos; Compostos Benzidrílicos/toxicidade; Feminino; Humanos; Simulação de Acoplamento Molecular; Fenóis; Placenta/metabolismo; Gravidez; Receptores dos Hormônios Tireóideos/metabolismo; Receptores beta dos Hormônios Tireóideos; Trofoblastos/metabolismo

Palavras-chave

BPA analogs; binding interaction; fluorescence spectrum; molecular dynamics simulation; thyroid hormone receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trofoblastos / Receptores dos Hormônios Tireóideos Tipo de estudo: Risk_factors_studies Limite: Female / Humans / Pregnancy Idioma: En Revista: Environ Sci Technol Ano de publicação: 2022 Tipo de documento: Article

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