Unfolding and aggregation of oxidized metal-deficient superoxide dismutase and isoflavone inhibition based on ion mobility mass spectrometry and ThT fluorescence assay.

Bian, Xinyu; Zhuang, Xiaoyu; Zheng, Zhong; Liu, Shu; Liu, Zhiqiang; Song, Fengrui

Bian, Xinyu; Zhuang, Xiaoyu; Zheng, Zhong; Liu, Shu; Liu, Zhiqiang; Song, Fengrui.

Afiliação

Bian X; State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130021, China; School of Applied Chemistry and Engineering, University of Science
Zhuang X; Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Zheng Z; State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130021, China.
Liu S; State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130021, China; School of Applied Chemistry and Engineering, University of Science
Liu Z; State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130021, China; School of Applied Chemistry and Engineering, University of Science
Song F; State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130021, China; School of Applied Chemistry and Engineering, University of Science

Arch Biochem Biophys ; 727: 109306, 2022 09 30.

Article em En | MEDLINE | ID: mdl-35667444

Assuntos

Esclerose Lateral Amiotrófica; Isoflavonas; Desdobramento de Proteína; Cobre/química; Humanos; Isoflavonas/farmacologia; Espectrometria de Massas; Metais; Mutação; Superóxido Dismutase/metabolismo; Superóxido Dismutase-1/metabolismo; Zinco/química

Palavras-chave

Amyotrophic lateral sclerosis; Glycitin; Ion mobility mass spectrometry; Metal-deficient superoxide dismutase; Oxidation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desdobramento de Proteína / Esclerose Lateral Amiotrófica / Isoflavonas Limite: Humans Idioma: En Revista: Arch Biochem Biophys Ano de publicação: 2022 Tipo de documento: Article

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