The antioxidant activities, inhibitory effects, kinetics, and mechanisms of artocarpin and &#945;-mangostin on &#945;-glucosidase and &#945;-amylase.

Wang, Qirou; Li, Ruilin; Li, Nannan; Jia, Yanan; Wang, Yajie; Chen, Yue; Panichayupakaranant, Pharkphoom; Chen, Haixia

The antioxidant activities, inhibitory effects, kinetics, and mechanisms of artocarpin and α-mangostin on α-glucosidase and α-amylase.

Wang, Qirou; Li, Ruilin; Li, Nannan; Jia, Yanan; Wang, Yajie; Chen, Yue; Panichayupakaranant, Pharkphoom; Chen, Haixia.

Afiliação

Wang Q; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Li R; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Li N; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Jia Y; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Wang Y; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Chen Y; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China.
Panichayupakaranant P; Phytomedicine and Pharmaceutical Biotechnology Excellence Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.
Chen H; Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China. Electronic address: chenhx@tju.edu.cn.

Int J Biol Macromol ; 213: 880-891, 2022 Jul 31.

Article em En | MEDLINE | ID: mdl-35688278

Assuntos

alfa-Amilases; alfa-Glucosidases; Antioxidantes/química; Antioxidantes/farmacologia; Inibidores de Glicosídeo Hidrolases/química; Hipoglicemiantes/farmacologia; Cinética; Lectinas de Ligação a Manose; Simulação de Acoplamento Molecular; Lectinas de Plantas; Xantonas; alfa-Amilases/química; alfa-Glucosidases/metabolismo

Palavras-chave

Antioxidant activity; Artocarpin; Inhibition mechanism; α-Glucosidase; α-Mangostin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Amilases / Alfa-Glucosidases Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2022 Tipo de documento: Article

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